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The journal · field notes

The journal.

Practical essays on modern experiment design and how AI now makes it accessible. Written for chemists, not statisticians.

  • Design of Experiments

    Every experiment is a point in the design space

    Every experiment is a point in the design space. Changing one factor at a time covers only the edges. A factorial design covers the whole space with the same handful of runs.

    2026 · 06 · 13
    8 min read
  • Lab Automation · AI

    Every experiment teaches something. The question is how much.

    Every lab runs experiments. What sets two labs apart is how much each one teaches. Four stages separate a lab that repeats itself from one that learns, each teaching more than the last.

    2026 · 06 · 07
    7 min read

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Ending trial and error in coatings R&D, one essay at a time.

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